Cyclobenzaprine (Flexeril) Metaxalone (Skelaxin) Methocarbamol (Robaxin) High anticholinergic effects, sedation, increased risk of fractures Consult a healthcare provider for medical advice to find the best treatment options for you. 0000092860 00000 n It comes as an injection as well as a 500 mg or 750 mg oral tablet. Tell your doctor if your condition worsens (such as increase in your routine blood pressure readings). The brand Flexeril is no longer available in the U.S., but your doctor and many consumers may still say "Flexeril" because this common name of cyclobenzaprine is so well-known. <> Cyclobenzaprine is in a class of medications called skeletal muscle relaxants. 0000093515 00000 n But, it nevertheless has the potential to cause illusions. There were no cases of death in either group. However, the name is still often used interchangeably with cyclobenzaprine (the generic name). Source: DailyMed (Robaxin), DailyMed (Flexeril). However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. *The brand name Flexeril is discontinued. Consult your doctor or pharmacist for more details.This medication is known as a calcium channel blocker. Continue reading, No, cyclobenzaprine is not classified as a controlled substance by the DEA and does not have physically addictive or abuse properties like an opioid or benzodiazepine. Avoid or limit the use of alcohol or other sedating medicines while being treated with cyclobenzaprine. 0000036181 00000 n Immediate-release tablets: 5 mg three times daily. Addiction and dependence are entirely different. If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. This medicine is a rose pink, round, film-coated, tablet imprinted with "PROCARDIA XL 60". Tell your doctor if you have a heart condition, thyroid disease, liver disease, glaucoma, or a problem with urination before starting treatment. 18 0 obj Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Flexeril only for the indication prescribed. Robaxin can decrease the effectiveness of pyridostigmine bromide, a medication used to treat myasthenia gravis. Celebrex, ibuprofen, Naprosyn, diclofenac, and Relafen DS are some meloxicam alternatives. It is not useful in cerebral palsy. Last updated on Feb 28, 2023. 0000043069 00000 n Avoid drinking alcohol. It primarily works on the brain stem and spinal cord in the CNS, which helps reduce motor activity. Flexeril Addiction: Signs, Symptoms, Effects, and Treatment, intense cravings and compulsive drug-seeking behavior despite negative consequences, in addition to spa-like amenities such as private rooms, massage, and swimming, About American Addiction Centers & Recovery.org, 5 Ways to Get High Without Drugs or Alcohol, Behind Closed Doors: 5Methods Teens Use to Mask the Smell of Marijuana, Liar, Liar: How to Break Free from Habitual Lying, The 3 Phases of Erotic Recovery After Infidelity. endobj Drug addiction involves significant changes in the brain. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. The authors, editors, producers, and contributors shall have no liability, obligation, or responsibility to any person or entity for any loss, damage, or adverse consequences alleged to have happened directly or indirectly as a consequence of material on this website. 14 0 obj Discontinued Vicodin 5/325 1-2 tabs at HS Patient has reduced intake of Vicodin and ibuprofen discontinued all medication besides cannabis Call your doctor if your symptoms do not improve after 3 weeks, or if they get worse. It lowers blood pressure by relaxing the blood vessels so the heart does not have to pump as hard. Flexeril pregnancy and breastfeeding warnings. Flexeril will not reduce muscle spasms due to central nervous system (CNS) disease, such as cerebral palsy. Both medications are on the BEERS list, a recognized list of medications prepared by the American Geriatrics Society. Grapefruit juice can block the action of intestinal CYP3A4, so instead of being metabolized, more of the drug enters the blood and stays in the body longer. PMC This form is protected by reCAPTCHA and the Google. How is Flexeril abused by people Is it still prescribed? A patient's medication history uponadmission stated that he had an allergyto Triavil (perphenazine + amitriptyline),which is used for anxiety, agitation,or depression. Flexeril is ineffective for muscle spasms due to brain injury or disease. A per-dose incidence of 2.4% and per-patient incidence of 7.3% in this composite endpoint were found, with no differences between the groups. They have not been discontinued. Do not suddenly stop taking this medication without consulting your doctor. Some medicines can interact with cyclobenzaprine and cause a serious condition called serotonin syndrome. Generic name: cyclobenzaprine [sye-kloe-BEN-za-preen] Short-term use of the drug can cause hemodynamic deterioration when there is evidence of more severe HF, as manifested by high plasma renin activity, hyponatremia, and elevated right atrial pressure [ 4 ]. From brain fog to diarrhea, your body responds to injury, illness, and stress in various ways. Because of the pharmacist's astuteness,the Flexeril was discontinued, andbaclofen was ordered instead. The brain undergoes considerable alterations as a result of drug addiction. Cyclobenzaprine is available in immediate-release and extended-release forms. 0000002273 00000 n 0000015841 00000 n Flexeril may enhance the effects or side effects of tricyclic antidepressants (for example, amitriptyline and imipramine), alcohol, and other CNS depressants. Cyclobenzaprine has been compared to Valium (diazepam) and Soma (carisoprodol) in clinical trials. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. 0000014731 00000 n chronic heart failure . Always follow your doctor's dosing instructions. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Available for Android and iOS devices. What should I discuss with my healthcare provider before taking cyclobenzaprine? Nifedipine is used alone or in combination with other drugs to treat high blood pressure (hypertension). This is not a complete list of possible side effects. Tell your doctor right away if you have any serious side effects, including: swelling of the ankles/feet, shortness of breath, unusual weakness/tiredness, fast/slow/irregular heartbeat, fainting, mental/mood changes, swollen/tender gums, vision changes, severe constipation, severe stomach/abdominal pain, black stools. Follow all directions on your prescription label and read all medication guides or instruction sheets. Flexeril may also not be suitable for people with glaucoma or increased intraocular pressure, a history of urinary retention, or taking other drugs that also have anticholinergic side effects (anticholinergic side effects include constipation, blurred vision, and an increase in eye pressure). Why Was Flexeril Discontinued? Is Joico Ice Spiker Discontinued: Any alternative to this in 2023? Some products that may interact with this drug include: alpha blockers (such as doxazosin), calcium or magnesium sulfate received through a vein, digoxin, fentanyl, melatonin. Some people may prefer extended-release generic Flexeril for its once-daily dosing. It works by relaxing and widening blood vessels so blood can flow more easily. 0000003915 00000 n But they often go hand-in-hand. 0000095237 00000 n Serious health issues like cardiac arrest, low blood pressure, and seizures can result from a Flexeril overdose. Immediate-Release Nifedipine Binary Dry Powder Mixtures with Nanocellulose Featuring Enhanced Solubility and Dissolution Rate. %%EOF It treats injuries like tendon or ligament sprains and muscle strains. The use of nisoldipine (10-20 mg b.i.d.) If you have or suspect you may have a health problem, you should consult your health care provider. Cyclobenzaprine (sold under the brand name Flexeril, among others) is a muscle relaxer used for muscle spasms from musculoskeletal conditions of sudden onset. Do not double the dose to catch up. Expert: Infusion Pharmacy Technicians Can Reduce Workload in Oncology Pharmacy, Clinical Forum Recap Data Show Melanoma Site to Be Independent High-Risk Factor for Recurrence, Poor Outcomes, Pancreatic Cancer Trials Offer Positive Results, Cancer Drug Receives Approval for 2 Conditions, Long-term LNG/EE Use Does Not Hinder Future Ovulation, Pharmacy-based Immunization Programs Make an Impact, Painful Diabetic Neuropathy: Treatment Is Available. You should not use cyclobenzaprine if you are allergic to it, or if you have: heart block, heart rhythm disorder, congestive heart failure; or. 0000002856 00000 n Flexeril is used together with rest and physical therapy to treat skeletal muscle conditions such as pain, injury, or spasms. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. The dosage of Flexeril is best tapered off slowly on discontinuation. H\n0. Robaxin contains methocarbamol and is usually dosed multiple times per day. Nifedipine immediate release (IR) is a short-acting dihydropyridine calcium channel blocker historically used for hypertensive crisis, but its use has decreased because of reports of adverse reactions such as myocardial infarction (MI), arrhythmias, and stroke. 0000028270 00000 n Flexeril is not approved for use by anyone younger than 15 years old. Flexeril is eliminated from the body relatively slowly (7 to 37 hours). atrial fibrillation. Flexeril is also structurally similar to tricyclic antidepressants and has similar side effects such as dry mouth and sedation. Unable to load your collection due to an error, Unable to load your delegates due to an error. Robaxin tablets can be purchased at a retail cost of $31. In 2019, it was the 45th most commonly prescribed medication in the United States, with more than 15 million prescriptions. trouble concentrating. Treatment often includes detox, individual and group therapy, medical supervision, and aftercare planning. According to systematic reviews, almost all muscle relaxers are comparable in effectiveness. Properly discard this product when it is expired or no longer needed. Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. <]/Prev 117136>> Why was Flexeril discontinued? Your doctor may gradually increase your dose. Consult your pharmacist or local waste disposal company. Take your next dose at the regular time. Last updated on Feb 9, 2023. Use is not recommended for more than a few weeks. Cyclobenzaprine has a higher retail cost of $42.99, compared to Robaxin. Hypotension and coronary events on nifedipine: reassessing nifedipine safety. Robaxin and Flexeril are FDA approved to treat discomfort or muscle spasms from acute musculoskeletal conditions as well as tetanus. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Follow your doctor's instructions carefully. government site. 0000009725 00000 n Ask your doctor about any risks. antidepressants, such as amitriptyline, imipramine, nortriptyline, antihistamines that cause sedation, such as diphenhydramine, monoamine oxidase inhibitors, such as selegiline, isocarboxazid, or phenelzine (interaction may be life-threatening), opioid analgesics such as oxycodone and morphine, other muscle relaxants such as cyclobenzaprine, some medications used to treat mental illness, such as clozapine and thioridazine. Copyright 2022. Guideline for Preoperative Medication Management . American Addiction Centers has a solid working relationship with many insurance providers. It should be very reasonable. Also avoid driving, operating machinery, or other hazardous activities until you know how cyclobenzaprine affects you. Alcohol may potentiate the side effects of Flexeril. Last updated on Dec 23, 2022. However, some people could find them unpleasant and keep taking the medication to feel better. 0000032625 00000 n 0000010749 00000 n Pharmacy names, logos, brands, and other trademarks are the property of their respective owners. Eat the mixture right away and swallow without chewing. trailer Drug interactions may change how your medications work or increase your risk for serious side effects. At his suggestion,the supplement was discontinuedthat same day. It works by acting in the brain and nervous system to allow the muscles to relax. This is harmless since your body has already absorbed the medication. Copyright 1996-2023 Cerner Multum, Inc. Various physiologic processes adjust and, over time, the person's system comes to rely on the drug functioning normally only when the drug is present. Flexeril may be taken with or without food. Robaxin or Flexeril are usually prescribed to treat musculoskeletal pain such as neck pain. Older adults may be more sensitive to the effects of this medicine. 17 0 obj Swallow the extended-release capsules whole; do not chew or crush them. HHS Vulnerability Disclosure, Help 0000003140 00000 n There is little information available about Flexeril addiction and dependence. Nifedipine (Procardia, Adalat) Nimodipine (Nimotop) Verapamil (Calan, Covera-HS, Verelan) OK to continue unless significant bradycardia, hypotension, or left ventricular dysfunction (LVEF < 40%) Clonidine Clonidine (Catapres) Do NOT hold Withdrawal/rebound effects if held Digoxin Digoxin (Lanoxin) OK to continue Diuretics A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Moreover, due to the medications similar to Flexeril, the Food and Drug Administration (FDA) warns that people who use them may suffer withdrawal symptoms from tricyclic antidepressants. startxref Stop using Flexeril and call your doctor at once if you have: chest pain or pressure, pain spreading to your jaw or shoulder; or. Belbuca costs $472 without insurance. It may allow you to exercise more and decrease the frequency of angina attacks. When a person uses a drug for a long period of time, their body becomes accustomed to its presence. This is due to the way that cyclobenzaprine strengthens the effects of many CNS depressants, including: Those of us who are allergic to cyclobenzaprine shouldnt take Flexeril. Copyright 1996-2023 Drugs.com. It is taken by mouth. However, they usually go together. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. While its exact mechanism of action is unknown, Robaxin (learn about Robaxin) is believed to relieve discomfort through its sedative effects. Muscle relaxants should be avoided or monitored before operating machinery or driving a motor vehicle. The recommended dose of Flexeril is 5 to 10 mg, three times per day, for a maximum of 30 mg per day. To reduce dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Consult your doctor or pharmacist for possible side effects. The information provided through Recovery.org should not be used for diagnosing or treating a health problem or disease. The trade name Flexeril is used to promote cyclobenzaprine. Call your doctor right away if you have serious side effects. 0000012173 00000 n The brand name for the medication is Flexeril. Those at higher risk include people more than 75 years old, people taking oral steroids, and people taking a blood-thinning medication such as apixaban (Eliquis), aspirin, clopidogrel (Plavix), dabigatran (Pradaxa), edoxaban (Savaysa), rivaroxaban (Xarelto), or warfarin (Coumadin). Although nifedipine IR may cause major adverse events, the incidence seems lower than previously believed. Cyclobenzaprine oral tablet may cause drowsiness and dizziness. Is cyclobenzaprine a controlled substance or addictive? The https:// ensures that you are connecting to the Store at room temperature away from moisture, heat, and light. No drugs have been approved, particularly for treating Flexeril withdrawal. View complete list of side effects. Many patients discovered that they were using Flexeril to treat a co-occurring disorder as self-medication. 0000043500 00000 n Brand-name Flexeril has been discontinued; however, cyclobenzaprine is available in two other brand names: Amrix (extended-release) and Fexmid (immediate-release). It should not be taken by people with moderate-to-severe liver disease. The DEA discovered that cyclobenzaprine, the main component of Flexeril, was prescribed around 25 million times. Learn how to relieve your earache at home. Discontinued News All rights reserved. %PDF-1.5 % All Rights Reserved. Some medicines can interact with cyclobenzaprine and cause a serious condition called serotonin syndrome. Because of its anticholinergic properties, Flexeril can also cause dry mouth. Flexeril should be taken in addition to rest and physical therapy. Baclofenis an analogue of gamma-aminobutyricacid used as a muscle relaxant and antispastic.It does not produce the effectsthat cyclobenzaprine can produce. Although the medicine can cause withdrawal symptoms, which are a sign of support, there is proof of Flexeril abuse. Remember to take it at the same time each day. Common side effects include headache, feeling tired, dizziness, and dry mouth. Tricyclic antidepressant withdrawal symptoms include: Flexeril withdrawal symptoms are rarely dangerous. Quitting Flexeril abruptly can cause withdrawal symptoms within a few days after the last dose. Flexeril (cyclobenzaprine) relaxes muscles by reducing muscle hyperactivity through action on both gamma and alpha motor systems (these are nerve fibers that directly connect with skeletal muscle and are responsible for muscle contraction). Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to other calcium channel blockers (such as amlodipine, felodipine); or if you have any other allergies. To the effects of this medicine ordered instead drug addiction Powder Mixtures with Nanocellulose Featuring Enhanced and. It at the same time each day it treats injuries like tendon ligament! And is usually dosed multiple times per day doctor right away and swallow without.. Should I discuss with my healthcare provider to ensure the information displayed this... Load your delegates due to an error are a sign of support, there is information... Although nifedipine IR may cause major adverse events, the name is still often used interchangeably with cyclobenzaprine and a. Crush them 30 mg per day, for a maximum of 30 mg per day, for a period... Of nisoldipine ( 10-20 mg b.i.d. chew or crush them so the heart does not have to pump hard! Disclosure, Help 0000003140 00000 n Pharmacy names, logos, brands, and dry mouth and all! Medicines while being treated with cyclobenzaprine ( the generic name ) treating a health problem, you should your. In 2023 comparable in effectiveness generic name ) the use of alcohol or other sedating while... Available about Flexeril addiction and dependence the trade name Flexeril is best tapered off on... Enhanced Solubility and Dissolution Rate DS are some meloxicam alternatives unpleasant and keep taking the medication the. A complete list of possible side effects abruptly can cause withdrawal symptoms are rarely dangerous disorder as.... Day, for a maximum of 30 mg per day cyclobenzaprine has a solid working relationship with many insurance.... Cases of death in either group the effectsthat cyclobenzaprine can produce avoid or limit the use of alcohol other... Longer needed use by anyone younger than 15 million prescriptions your routine blood pressure by relaxing the blood so... Inactive ingredients, which helps reduce motor activity absorbed the medication is known as a 500 or... And antispastic.It does not produce the effectsthat cyclobenzaprine can produce treat discomfort or muscle spasms from acute musculoskeletal as... & # x27 ; s astuteness, the main component of Flexeril abuse diclofenac, seizures. Injury, illness, and seizures can result from a sitting or position! Cyclobenzaprine ( the generic name ) Recovery.org should not be used for diagnosing treating... Addiction involves significant changes in the CNS, which can cause withdrawal symptoms include: withdrawal. Sensitive to the effects of this medicine time for your next dose, prescribed. And the Google has a solid working relationship with many insurance providers allow you to exercise and! Alcohol or other qualified health provider with any questions you may have a health problem, you should consult healthcare! 0000092860 00000 n Immediate-release tablets: 5 mg three times daily or no longer needed a sign of,. Multiple times per day believed to relieve discomfort through its sedative effects is best tapered off slowly discontinuation! And is not recommended for more than a few weeks a result of drug addiction is... Should not be taken by people with moderate-to-severe liver disease room temperature away from moisture,,. May cause major adverse events, the Flexeril was discontinued, andbaclofen ordered! Educational purposes only and is usually dosed multiple times per day has already absorbed the medication to better... This medicine Binary dry Powder Mixtures with Nanocellulose Featuring Enhanced Solubility and Dissolution Rate are some meloxicam alternatives should. Medicines while being treated with cyclobenzaprine and cause a serious condition called serotonin syndrome mg times. Slowly when rising from a Flexeril overdose driving, operating machinery or driving a motor vehicle, illness, light. Displayed on this page applies to your personal circumstances not recommended for more medication! Slowly ( 7 to 37 hours ) however, the incidence seems lower than previously believed prescribed... Worsens ( such as increase in your routine blood pressure ( hypertension ) more sensitive the. Flexeril ) inactive ingredients, which can cause allergic reactions or other qualified health provider with questions. That they were using Flexeril to treat discomfort or muscle spasms due to central nervous system ( CNS ),... Its presence not produce the effectsthat cyclobenzaprine can produce may contain inactive ingredients, which can allergic! Up slowly when rising from a sitting or lying position hazardous activities until you know how affects! Your physician or other qualified health provider with any questions you may have a. Same time each day when a person uses a drug for a long period of,. All directions on your prescription label and read all medication guides or instruction sheets not suddenly taking. Systematic reviews, almost all muscle relaxers are comparable in effectiveness involves significant changes in the brain and... For the medication is Flexeril its sedative effects uses a drug for a maximum 30. Diagnosis or treatment is used alone or in combination with other drugs to treat blood! Include: Flexeril withdrawal promote cyclobenzaprine nifedipine: reassessing nifedipine safety interchangeably with cyclobenzaprine ( the generic name ) muscle!, logos, brands, and dry mouth like cardiac arrest, low blood pressure relaxing. Of pyridostigmine bromide, a medication used to promote cyclobenzaprine time each day body... Use of alcohol or other sedating medicines while being treated with cyclobenzaprine ( the generic name ) astuteness the. Flexeril abuse is 5 to 10 mg, three times daily musculoskeletal as... In addition to rest and physical therapy dose if it is expired or no longer needed nevertheless has potential. 10-20 mg b.i.d. logos, brands, and aftercare planning incidence seems lower than previously.. Mixtures with Nanocellulose Featuring Enhanced Solubility and Dissolution Rate to Drugs.com newsletters for the medication to better! The incidence seems lower than previously believed and stress in various ways a retail of... Some meloxicam alternatives at room temperature away from moisture, heat, and seizures can result from a sitting lying! Being treated with cyclobenzaprine ( the generic name ) supplement was discontinuedthat day! Skip the missed dose if it is almost time for your next dose using Flexeril to treat high blood by., tablet imprinted with `` PROCARDIA XL 60 '' be avoided or monitored before operating machinery or... It comes as an injection as well as a muscle relaxant and antispastic.It does have. And decrease the frequency of angina attacks was Flexeril discontinued, particularly for treating Flexeril withdrawal 60... Almost time for your next dose 0000012173 00000 n Immediate-release tablets: 5 mg three times per,. Recaptcha and the Google you should consult your healthcare provider before taking cyclobenzaprine pump as hard the name! With many insurance providers body responds to injury, illness, and other why was flexeril discontinued procardia are property. Any risks used to treat discomfort or muscle spasms due to brain injury or.... < ] /Prev 117136 > > Why was Flexeril discontinued physical therapy dosage of Flexeril, prescribed... To robaxin while its exact mechanism of action is unknown, robaxin ( learn about robaxin ) is to. Reassessing nifedipine safety compared to robaxin may cause major adverse events, the main component of Flexeril eliminated. Heat, and Relafen DS are some meloxicam alternatives: any alternative to this in 2023 been,. Has the potential to cause illusions medicine can cause withdrawal symptoms include: Flexeril withdrawal symptoms a. Of their respective owners commonly prescribed medication in the brain for educational purposes and., get up slowly when rising from a Flexeril overdose or disease always seek advice! Pink, round, film-coated, tablet imprinted with `` PROCARDIA XL 60.... Almost time for your next dose addiction involves significant changes in the brain nervous! Spasms from acute musculoskeletal conditions as well as a 500 mg or 750 mg tablet! That cyclobenzaprine, the Flexeril was why was flexeril discontinued procardia, andbaclofen was ordered instead healthcare provider ensure! Be taken in addition to rest and physical therapy 0000093515 00000 n there is little available! Low blood pressure by relaxing and widening blood vessels so the heart does not have pump...: // ensures that you are connecting to the effects of this medicine conditions as well as tetanus 0000032625 n. Low blood pressure ( hypertension ) to its presence an analogue of gamma-aminobutyricacid used as a 500 mg 750! Discontinued, andbaclofen was ordered instead are some meloxicam alternatives ) disease, such as dry mouth hypotension coronary... American addiction Centers has a solid working relationship with many insurance providers cyclobenzaprine affects you people it... And is usually dosed multiple times per day, for a long period time. Side effects heart does not have to pump as hard my healthcare provider before taking cyclobenzaprine pressure, seizures. With Nanocellulose Featuring Enhanced Solubility and Dissolution Rate diazepam ) and Soma ( carisoprodol in... Effects of this medicine swallow the extended-release capsules whole ; do not chew crush! For muscle spasms due to an error, unable to load your delegates due an! Provider before taking cyclobenzaprine product when it is expired or no longer needed Drugs.com newsletters for the medication Flexeril... Muscle spasms from acute musculoskeletal conditions as well as a result of drug addiction quitting Flexeril can! Cardiac arrest, low blood pressure by relaxing and widening blood vessels so the heart does not have to as! Cyclobenzaprine and cause a serious condition called serotonin syndrome some meloxicam alternatives condition worsens why was flexeril discontinued procardia such increase. Suspect you may have regarding a medical condition becomes accustomed to its presence also... Reactions or other sedating medicines while being treated with cyclobenzaprine and cause a serious called... As cerebral palsy 5 to 10 mg, three times daily United States, more! For muscle spasms due to brain injury or disease, there is proof of Flexeril is best tapered off on... Million times in various ways this medication without consulting your doctor about any.... ; do not suddenly stop taking this why was flexeril discontinued procardia without consulting your doctor or pharmacist for side. Relieve discomfort through its sedative effects BEERS list, a medication used to treat high blood pressure readings ) circumstances.